The Department of Pharmacy of Jiangsu Province Hospital，formerly known as dispensing pharmacy，herb-medicine pharmacy and pharmaceutical preparation pharmacy in the hospital，now setting up dispensing division，medicine operation centre division as well as clinical pharmacy division and establishing pharmacology research lab，is famous for the key speciality of clinical pharmacy of Jiangsu,the key disciplines of clinical pharmacy of Nanjing Medical University,the clinical pharmacy department of College of Pharmacy in Nanjing Medical University,National Health and Family Planning Commission ‘clinical Pharmacist system’ pilot hospital,National Health and Family Planning Commission clinical pharmacist training pilot hospital,Jiangsu province Qiang Wei project innovation team ,Jiangsu province clinical trial service center of cardiovascular medicine and antiviral medicine,‘12th Five Year Plan’construction hospital of clinical research platform for new drugs for respiratory diseases and standardized treatment of cancer pain demonstration hospital.
There are 139 workers in the department, including 1 doctoral supervisor,6 master's supervisor, 5 with doctoral degree,16 with master’s degree, 26 with title of a senior professional post as well as 2 with Revitalizing the key talent's subsidy project,2 with Six talent peaks project in Jiangsu Province,1 with 333 high level talents project in Jiangsu Province In the past few years, the department has undertaken 10 projects funded by the National Natural Science Foundation of China, more than 20 projects funded by Jiangsu Province and published more than 60 SCI theses,achieving features and advantages in clinical PK-PD pharmacogenomics research about innovative drug,clinical pharmacy education and continuing education, adverse reaction monitoring, supply logistics system of medicine and reagent. The academic leaders and key members of the department hold the post of chair/vice chair of national/provincial association committees as well as chief editor or associate editor in national/provincial journal，having high academic influence in China.
Chinese Communist Party Member
Director of Pharmacists
Master's Supervisors of Nanjing Medical University
Dr.Meng is working as the director, pharmacy department of Jiangsu Province Hospital and also the department of clinical pharmacy, Nanjing medical university. Over the years she committed herself to the development and research of pharmaceutical cause, especially in the aspect of clinical pharmacy and now she is an accomplished pharmaceutical professional with years of experience. Dr. Meng published more than 10 papers in international academic journals and 60 papers in Chinese core journal. She completed nearly10 national and provincial scientific research projects and also accomplished more than 10 books these years. Main Professional Affiliations: Director, Chinese Pharmaceutical Association; Member, Professional committee of the Chinese hospital pharmacy; Member, pharmaceutical affair management committee of Chinese Hospital Association; Former director, Clinical pharmacy chapter of jiangsu province medical association;Deputy Secretary-General, Jiangsu Province Pharmaceutical Association; chairman, hospital pharmacy committee of jiangsu province Pharmaceutical association; vice-chairman, pharmacoeconomics society of jiangsu province Pharmaceutical association; vice-chairman, pharmaceutical affair management committee of Jiangsu Hospital Association; director,pharmaceutical affairs management and quality control centre; director, Pharmacist association in jiangsu province; vice-chairman, Nanjing Pharmaceutical Association; chairman, Nanjing hospital pharmacy committee. Dr.Meng is also served as chief editor of many magazines such as the China pharmacy, Journal of clinical rational drug use, Drug and clinical research, Journal of Chinese Hospital pharmacy.
She is experts,Ministry of health's National Popularization program of clinical rational use of antibiotics as well as clinical pharmacy research project of provincial medical science and technology development fund. She has won many awards and was voted the excellent pharmacist nationwide and Jiangsu province.
1. Therapeutic Drug Monitoring
The therapeutic drug monitoring room of pharmacy department equipped with the advanced automatic immunoassay analyzer Architect i1000 and drug concentration analysis system siemens viva-e. We carried out about more than 11 therapeutic drugs monitoring including cyclosporine, FK506, rapamycin, digoxin, valproate sodium, carboplatin, theophylline, phenytoin, vancomycin, methotrexate, mycophenolate and so on. With the help of therapeutic drug monitoring, we maked a closely relationship with the clinical doctor, and help the patients to use drugs individually. With the strict quality control system, regulation system and Standard Operating Procelure, we ensured the internal quality control and external quality assessment. Another way, with all these, the accuracy and reliability of the laboratory data of therapeutic drug monitoring was ensured.From 2012 to now, more than 47000 blood samples were tested. The variety and quantity of samples all taked the leading position in our country. It provided the therapeutic drug monitoring of immune inhibitors and administration design for transplant patients. It improved the surgery success rate and prolonged the patient survival.
The genetic polymorphism is the main reason for affecting the efficacy and safety of drugs. The pharmaeogenomies analysed the genetic factors effect to efficacy and safety of drugs by detecting the variation of metabolic enzymes, transporters, targets in patients. Then, We provided helpment for clinicians to develop Individualized dosage regimen, and achieved Precision medical treatment.
The pharmacogenomics section carry out the detection of genetic polymorphisms of 26 medcines including warfarin, clopidogrel, proton pump inhibitors, cytarabine, methotrexate, cyclosporine A, tacrolimus, sirolimus, mycophenolate, allopurinol, carbamazepine, phenytoin, lamotrigine, glucocorticoid and etc., on the base of which clinical pharmacists analyze comprehensively with their professional skills, the influence of heredity, pathology, individuality and combined medication on treatment. The reports of pharmacogenomics could help physicians with individualized medication.
Since the launch of this project in October of 2014, over 2000 patients have received the detection of genetic polymorphisms and more than 500 individualized medication plans have been designed, with the cooperation between pharmacy and several clinical departments, which has provided reference for precision medication and has been highly praised by them. Currently, Jiangsu Province Hospital has occupied a leading position in the number of detectable medicines and gene loci, and the design of individualized medication plans in China.